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Professor Cyril Lennox Moore became
a recognisable name at the famous Albert Einstein
College of Medicine, the university with the largest
postgraduate medical training programme in the United
States of America. He was also a founding faculty
member at the Morehouse School of Medicine and a
pioneer in mitochondrial research[1]
before it became an established field of study.
Moore was born on 14th February,
1928 in Tunapuna, Trinidad. He received his primary
education at Tunapuna E.C. School and went on to
Queen’s Royal College. After leaving secondary school,
he worked with the postal service as a clerk until
1950, when he immigrated to the United States to
further his studies. He completed his Bachelor of Arts
(BA) degree in Chemistry at Brooklyn College, New York
in 1953. After graduating, he was called to serve the
United States Army but received an honourable discharge
due to disability, and proceeded to pursue his Master
of Arts (MA) degree in Chemistry at Brooklyn College in
1958.
In 1964, Moore obtained his
Doctorate (PhD) in Neurology and Biology from the
Albert Einstein College of Medicine in New York,
specialising in cellular energy production in the
nervous system. He pursued his post-doctorate studies
at the Johnson Foundation at the University of
Pennsylvania in Philadelphia. There, he contributed to
an internationally famous study on the antibiotic
valinomycin[2], showing
that it forced mitochondria to absorb potassium rather
than power the cell. He returned to the Albert Einstein
College in 1965 to serve as Instructor, rising to
Fellow and finally becoming Assistant Professor of
Neurology and Biochemistry until 1970, when he left for
Texas.
After spending three years as
Professor of Biochemistry and Pediatrics at the Medical
Branch of the University of Texas, Galveston, Moore
returned to the Albert Einstein College of Medicine as
Associate Professor of Neurology, Biochemistry and
Neuroscience and Professor of Biology and the
Biomedical Programme. In 1972, a post-doctoral trainee
under his supervision, Wendy Cammer, discovered that
the liquid cleanser pHisoHex was harmful. The chemical,
which had previously been used in new-born nurseries,
caused mitochondria to take up oxygen without producing
adenosine triphosphate[3]
(ATP) essentially starving the brain’s cells to death.
Dr Moore also conducted research on the obscure
Zellweger’s syndrome[4]
and mentored many up-and-coming neurologists during his
time at the College.
In 1976, he relocated to the
Morehouse School of Medicine in Atlanta. He was a
highly esteemed Professor and Chairman of the
Biochemistry Department until his retirement in 1999.
On the 12th February 2000, the Cyril L. Moore
Scholarship for medical students was created at
Morehouse as a testament to his dedication to education
and the great respect that he commanded from his peers
at that institution.
Professor Moore served on many state
boards, advisory boards and academic council committees
including the American Chemical Society, the Beta Kappa
Chi (Biology Honor Society), the National Organization
of Black Chemists and Chemical Engineers, the Alpha
Kappa Alpha Biology Honor Society and the Alpha Omega
Alpha Medical Honor Society. He also authored numerous
books, articles and other publications, and was a
highly regarded speaker.
Professor Cyril Moore passed away on
22nd February, 2006 at the age of 76.
1-The
mitochondrion is a cellular structure that serves as
the centre of energy production and the producer of ATP
in the cell
2-This chemical is no longer
an antibiotic. Now classified as hazardous, it is used
as an insecticide
3-Cells synthesise ATP
molecules to store energy and break ATP molecules down
to release energy
4-Zellweger’s syndrome is a
rare disorder marked by the reduction or absence of the
cellular structures that rid the body of toxic
substances in the liver, kidneys and brain
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